5′-Chlorospiro[1,3-dioxolane-2,3′-indolin]-2′-one: a potential anticonvulsant
نویسندگان
چکیده
منابع مشابه
Spiro[1,3-dioxolane-2,3′-indolin]-2′-one
The title compound, C(10)H(9)NO(3), was synthesized by the condensation reaction of isatin (systematic name 1H-indole-2,3-dione) with glycol in presence of p-toluene-sulfonic acid. The indol-2-one ring system is essentially planar [N-C-C-C torsion angle = 3.1 (2)°], and the 1,3-dioxolane ring is slightly distorted. The crystal structure exhibits inter-molecular N-H⋯O hydrogen bonds.
متن کامل5′-Chlorospiro[1,3-dioxolane-2,3′-indolin]-2′-one: a potential anticonvulsant
The title compound, C(10)H(8)ClNO(3), is a significant anti-convulsant agent. The indolinone system is essentially planar, the dihedral angle between the rings being 2.24 (8)°. The dioxolane ring adopts an envelope conformation; the dihedral angle between the plane through its four coplanar atoms and the indolinone system is 89.8 (1)°. The crystal structure is stabilized by a three-dimensional ...
متن کامل(E)-3-(2-Hydroxy-5-methylphenylimino)indolin-2-one
In the title compound, C(15)H(12)N(2)O(2), the dihedral angle between the two benzene rings is 83.55 (11)° In the crystal, the molecules are linked by O-H⋯O and N-H⋯O hydrogen bonds.
متن کامل5-Chlorobenzothiazole-2-spiro-3′-indolin-2′-one
The title compound, C(14)H(9)ClN(2)OS, crystallizes with two unique mol-ecules, A and B, in the asymmetric unit. The five-membered rings of the benzothia-zole groups in both mol-ecules adopt an envelope conformation [puckering parameters: q(2) = 0.242 (1) Å and ϕ(2) = 217.5 (4)° for A, and q(2) = 0.234 (1) Å and ϕ(2) = 37.7 (4)° for B]. The five-membered rings of the indolinone groups in both m...
متن کامل5-Fluoro-3-(2-phenylhydrazinylidene)indolin-2-one
In the title compound, C(14)H(10)FN(3)O, the six- and five-membered rings of the isatin moiety and the six-membered ring of phenyl-hydrazone are nearly planar with r.m.s. deviations of 0.0003, 0.0004 and 0.007 Å, respectively. The dihedral angle between the phenyl ring and the isatin ring system is 6.09 (9)°. The mol-ecular structure is stabilized by a strong intra-molecular N-H⋯O hydrogen bond...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2008
ISSN: 1600-5368
DOI: 10.1107/s160053680800336x